Entrancemperium is a black metal project from Punta Arenas, Chile — a city the band describes as "the end of the world" in reference to its remote location at the southern tip of the continent. Formed in January 2020, the band released their debut DEMO MMXXIV in February 2024, a two-track instrumental release in the black metal tradition.

EntreCruces is a black metal/punk band from Bogotá, Colombia, formed in 2020. Describing themselves as "Punk Negro del Centro profundo," the band channels anti-capitalist and anti-patriarchal themes through their raw, underground sound. Their catalog includes the releases "Bazuco" and a self-titled record, both available on their Bandcamp page.

Enucleacion is a death/grind band from Santiago, Chile, operating in the city's underground extreme metal scene. Their debut Demo 2020 was released in December 2020 through Santiago-based underground label Burning Coffin Recs, pressed to a limited run of 100 cassettes with distribution split between Chile and the United States. The label described their sound as a "rotten and chaotic" death/grind assault.

Enxöfre is a blackened heavy metal project from São Paulo, Brazil. The band released their debut album "Left Hand Path" in 2020 through Cianeto Records, a five-track effort blending black and heavy metal elements.

Epicedio is a progressive metal band from Montevideo, Uruguay, that formed in 2009 and released their debut full-length, Lacisum, in December 2018. The album spans nine instrumental tracks drawing on the complex arrangements and technical musicianship associated with acts like Dream Theater and Andromeda. The band operates independently out of Montevideo's underground metal scene.

Epifisis is a heavy metal band from Medellín, Colombia, formed in 2020 and rooted in the sounds of '70s and '80s heavy metal and hard rock. The band released their debut EP "6402 Sin Futuro" in 2021, a three-track release that deals with themes of social protest, violence, and society. They operate independently and are listed on Metal Archives under the genre Heavy Metal.

Epitafio is a death metal band from Maracay, Venezuela, that emerged in 2016. Their debut release, the digital EP III Operis Tertium (2016), delivers four tracks of punishing, riff-driven death metal with Latin-language track titles reflecting dark and hellish themes. The band operates independently out of the Aragua state metal underground.

Epochal is a progressive/post-metal band from Buenos Aires founded in 2013 by guitarists Daniel Bermúdez and Gustavo Cirigliano. The band recorded their debut album Awakening in late 2015 and early 2016 with drummer Tulio Salvatierra, releasing it in 2016.

Equidnos is a Black/Doom Metal band from Quito, Ecuador rooted in occultist themes. The project released its debut full-length, "Una larga noche de nekromancia 'Kuddesiell Konsinnatio Korporis'", in 2019 through Wolfgang Records, followed by the EP "Instrumentos para medir el viento" in 2021.