Encoffined is an old-school death metal band from Córdoba, Argentina, formed in 2015 and deeply influenced by the Swedish death metal scene of the 1990s — particularly Entombed, Dismember, Carnage, and Grave. The band has released three full-lengths: Enclosed in a Coffin (2015), Casket Citadel (2019, on Disembodied Records), and Cloak of Despondency (2021), with a lineup including vocalists Leandro Smith and Leonardo Gonzales, guitarist Juan Taricco, bassist Facundo Urriche, and drummer Marcos Cordoba.

Endeathed is a black metal band from Bogotá, Colombia, formed in 2018 and placed on hold in 2022 after releasing material through Azermedoth Records. Their discography includes the 2018 debut "A Deafening Void", the 2020 release "SEVEN", and the 20-track 2021 album "Deus/truction", with lyrical themes centered on darkness, death, occultism, and misanthropy.

Endless Sacrifice is a death metal band from Fray Luis Beltrán, Santa Fe, Argentina, whose music incorporates Christian lyrical themes — a relatively uncommon combination in the Argentine extreme metal underground. Their album End Transmission was released on January 23, 2017, and the band has been active on Bandcamp under independent and Lament Records releases.

Endless Sedition are a death metal band from Santiago formed in 2018, drawing comparisons to Immolation with their blend of brutality, haunting atmosphere, and eerie melodic build-ups. Their discography includes the 2019 EP Perpetual Sedition, a 2021 three-way split Imminent Death with Deconsekrated and Unbowel, and the forthcoming EP Sinister Devastation.

Endrah is a São Paulo, Brazil band playing a self-described fusion of death metal, thrash, and hardcore — billed as "Extreme Fight Metal" — founded in 2002 under the name INK before adopting the Endrah name in 2004. The band has headlined eight national tours of Brazil, supported acts including Hatebreed and Brujeria, and released their third full-length album "Bloodshed and Violence" in February 2025.

Enforcation is a death metal band from Sorocaba, São Paulo, Brazil, formed in 2014. The band plays old-school death metal with lyrical themes centered on gore, horror, and suffering, and released their debut EP "Pits Ov Fire and Torment" in 2015.

Enigma Ex Machina is an extreme progressive metal band from São Paulo, Brazil, formed in 2020 by André Vaz and Renato "Timbó" Machado, later expanded with drummer Artur Guedes and bassist João Castañon. The band explores lyrical themes of mental health and astronomy, and released their EP "The Event Horizon" in December 2020.

Enorion is a symphonic power metal band from Tatuí, São Paulo, Brazil. The band released the single "Vis Divina" in 2022 featuring a guest appearance by Fabio Lione of Rhapsody of Fire fame, and served as support for Lione's Epic Tales Brasil Tour in 2025.

Enot is a heavy/speed metal and hardcore band from San Pedro, Buenos Aires province, active since 2006 and signed to Escoria Records. The band contributed tracks to several Argentine underground compilations, including appearances on Ultrametal CD (1995), Hardcore Sin Fronteras Tape (1997), and Tributo a La Polla CD (2002) under an earlier formation, before reforming in 2019.