Dark Ember is a melodic death metal band from Buenos Aires, Argentina, formed in 2016, whose lineup includes vocalist Leo Lopez, guitarists Ernesto "Tito" Gonzalez and Martin Guidali, bassist Ivan Carrasco, and drummer Nicolas Candia. The band released their album "Behind Oddities" in 2019, blending melodic death metal with progressive elements.

Deadly Curse is a metal band from Goiânia, in the midwest of Brazil, originally formed in 2005 with the intent of playing aggressive and technical thrash metal before evolving into melodic death metal. Their discography includes a self-titled demo (2007), the full-length "Renegade" (2010), and the EP "Synthetic Humanization" (2013). The band remains active and independent, with lyrical themes centered on internal struggles and positivity.

Dehumanized was a melodic death metal band from Concepción, Bio Bío, Chile, active until splitting up. The band operated as an independent, unsigned act within the regional extreme metal underground of central-southern Chile.

Demencia Extrema is an extreme metal band from Ituzaingó in the western greater Buenos Aires area, drawing on metalcore, death metal, and 1990s groove metal influences. The band released the EP Mundo Ruin in August 2015, a five-song record recorded and mixed by FedeSaurio Records in Castelar-Morón, Buenos Aires, with composer Matias Chao as a key creative force.

Destino Eterno is a melodic death metal and metalcore band from Concepción, Chile, formed in 2016. The band debuted the same year with their "Contracorriente" EP, a six-track release featuring songs sung in Spanish that blend melodic death metal riffing with metalcore structures. They are signed to the Vessels Space label.

Disrupcion is a melodic death metal band from Salta, Argentina, founded in 2017. Their debut album "Introspectiva" was released in February 2019, comprising nine tracks recorded, mixed, and mastered at Áureo Estudio in Salta between June and November 2018.

Diva Satanica is a melodic death metal band from Rosario, Argentina, whose debut album "In the Reign of Death... I Monarch" was recorded at Venus Records Studios in 2009. They followed it with "II The Grand Successor" (2012) on Undermetal Records and "From the Ashes" (2015), before releasing the concept album "Germania: The Rise and Fall", which centres on World War II-era themes.

Divine Uncertainty is a melodic death metal band from São Paulo, Brazil, formed around 2012 and currently active. The band operates as an independent, unsigned act and has maintained a presence on platforms such as ReverbNation and Encyclopaedia Metallum. They contribute to the melodic death metal scene in Brazil's largest city.

Drastyca is a melodic death metal band from Cruz das Almas, Bahia, Brazil. The band released their debut EP Emblems in 2018, which was made widely available on digital platforms in 2020, and contributed the track Lake of Blood to the Roadie Metal Vol. 14 compilation.