Lazaro is a thrash metal band from Rafael Castillo, Buenos Aires, founded by guitarist Jorge Moreno following his departure from the long-running Argentine thrash act Serpentor. The band carries on the tradition of socially and politically charged thrash metal from the Greater Buenos Aires underground scene.

Legacy of Kain is a groove and thrash metal band from Curitiba, Paraná, Brazil, featuring guitarists Angelo Torquetto and Karim Serri, both veterans of bands including Doomsday Hymn and Desertor. The band released their debut album I.N.V.E.R.S.O in 2017, sung entirely in Portuguese, followed by Paralelo XI in 2019, and has toured Argentina as part of regional metal festival circuits.

Legion is a thrash metal band from La Plata, Argentina, whose lineup includes Nicolas Liendo on guitar and vocals, Rafael Garritano on guitar, Sergio Carrizo on drums, and John Williams on bass. Their debut album "Gran Mal" was recorded and mixed at Dormir Sucio studio in Berisso during 2016 and released in 2017. The band draws on the tradition of Argentine thrash acts such as Hermética and Horcas.

Lei do Cão is a crossover thrash band from Mossoró, Rio Grande do Norte, Brazil, formed in 2008. Their debut full-length Possuído pelo Tubarão was released in September 2008, delivering eight tracks of fast, aggressive crossover blending thrash and hardcore punk. The band also appeared on a split release with Crippled Fox in 2011, cementing their place in the Brazilian underground crossover scene.

Letargia is a crossover/doom/thrash metal band from Campo Limpo Paulista, São Paulo, Brazil, formed in 2001 and associated with Kill Yourself Productions. The band released the "Stragado EP" in November 2006, recorded at The Magic A.S.O.M. studio with founding members Pacu on guitar and vocals and Mindu on drums. Their music mixes crossover thrash with doom-inflected heaviness and themes of sex, drugs, and rock 'n' roll.

Lethal Blaster is a thrash/speed metal band from Arequipa, Peru, formed in 2013 and active on the local scene since 2015. The band released their self-titled EP in 2018 and followed it with their debut full-length "Velocidad sangrienta" in 2024, cementing their position in Peru's southern thrash scene.

Lethal Infection are a black/death/thrash metal band from Santiago, Chile, who began releasing material in 2017 with the demo Holy Pervertor and quickly followed it with a second demo, The Chant of the Black Prophecies. The band appeared on the split CD Morbid Chants from Southamerican Abyss alongside Putrid, released through Morbid Skull Records.

Leviaethan is one of the most storied thrash metal acts out of Porto Alegre, Rio Grande do Sul, with roots stretching back to 1983. The band released their debut album "Smile!" in 1989–1990 through Rock Brigade Records, followed by "Disturbed Mind" in 1992, and have remained active for over four decades as a cornerstone of Brazilian thrash metal.

Life in Grave is a thrash/crossover hardcore band from Ceilândia, in Brazil's Federal District, formed around 2019–2020 by André Sodom. The band released the debut EP "Graveweed" in 2020 and later appeared on the four-way split "Play Fast Ride Easy", delivering Sodom and Kreator-influenced riffs alongside themes of death and counterculture.