1000 Odios is a thrash and melodic death metal band from Mar del Plata, Argentina, with a lineup featuring vocalist Mayra Cortez alongside guitarists Esteban Magnano and Nicolas Palenzola. The band has released two full-lengths, Te Detesto (2016) and Placebo & Terror (2021), the latter produced and mixed by Juan Ignacio Ibáñez at Estudios Dadson.

Abyssall was a one-man melodic death metal project from Londrina, Paraná, Brazil, conceived and executed entirely by multi-instrumentalist Bruno Eduardo. Their 2022 debut EP "Victory Can Wait Forever" delivered five tracks wrestling with themes of technology, mass control, and guarded optimism, blending melodic death metal structure with introspective lyrical content before the project ceased activity.

Akaamelda is a one-man melodic death metal project from Buenos Aires, created by Alexey Ermakov, that draws on the classic Scandinavian style of the genre. The debut album Death Equals Relief was released in November 2024, followed by the expanded Epitaph Edition in March 2025, featuring thirteen tracks built around melodic guitar harmonies, heavy riffs, and themes of grief and despair. The project blends melancholic atmosphere with the high-energy drive of early 1990s melodic death metal.

Alpha Scorpii was a melodic death metal band from Varginha, Minas Gerais, whose lineup included guitarists, a keyboardist, and a bassist working within the Gothenburg-influenced style prominent in Brazilian melodeath circles. Their 2006 EP "Crimson Sting" stands as their documented output before the band eventually split up.

Arcaico formed in Avellaneda in the greater Buenos Aires area with a lineup of Adrián Saladino on vocals, Miguel Bustos and Demian Yanelli on guitars, Nico Meire on bass, and Federico Gusso on drums. The band released their self-titled EP in February 2013 through Black Eclosion Digital Record Label, a four-track effort that included the tracks "Tu Cabeza Es Mi Bandera" and "Revolución". Their sound blended melodic death metal riffing with aggressive rhythms rooted in the Argentine extreme metal underground.

Arcanen (originally active as Arkanen from 2003 to 2009) was a melodic death metal band from Antofagasta, Chile. The five-piece lineup featured Gonzalo Jara on vocals, César Aranda on bass, Eduardo Cuadra on guitar, Javier López on guitar and vocals, and Víctor Gutiérrez on drums. The band released the six-track EP Points of Projection in 2006, drawing comparisons to Swedish melodic death metal acts such as Dark Tranquillity and At the Gates.

Away from the Sun is a modern metalcore band from Curitiba, Paraná, Brazil, formed in 2020. Blending melodic death metal with contemporary metalcore, the band weaves themes of psychoanalytic archetypes, philosophy, and misanthropy throughout their releases, including the albums Unity and Anima. Their sound draws on the melodic Gothenburg tradition while incorporating the rhythmic aggression of modern metalcore.

Ação Negro is a melodic death metal band from Duque de Caxias, Rio de Janeiro, writing all their lyrics in Portuguese around themes of social contestation, ideological conflict, and existential struggle. Formed in 2016, the band blends melodic death metal structures with the social commentary more often associated with Brazilian hardcore, carving out a distinctive identity in the Rio de Janeiro metal underground.

Before Breathing is a melodic deathcore band from Chile who emerged in 2017 and gained an international following through intense live performances and sonically dense recordings. The band toured the United States in 2019, covering four states, and has drawn comparisons to acts such as Lorna Shore and Shadow of Intent. Their discography includes the debut EP Born Into the Chaos (2017) and the full-length Eternal Shadow of Existence (2022).