Destitution was a brutal death metal and grindcore band from Bauru, São Paulo, Brazil, catalogued on Encyclopaedia Metallum with gore-themed lyrical content. The band has since split up and is counted among the underground extreme metal acts that emerged from the interior of São Paulo state.

DestroyTheHumans is an Argentine grindcore band featuring El Podrido on vocals, Walter on guitars and bass, and Marcelo on drums. The band released the split album Hostis Humani Generis in February 2014 on Coche Bomba Records, paired with US grindcore act Dirty Mike & The Boys, contributing four tracks including "Lead Us" and "Anthem of Negativity."

Deuszebul is a grindcore, crust punk, and raw black metal band from Natal, Rio Grande do Norte, Brazil, active since 2014. The band has released a substantial catalog on Bandcamp including the albums "Mantra Invertido" (2014), "Abandono" (2017), and "Ao medonho eu entrego a degeneração de sua imagem" (2020), and contributed to the 2020 compilation "A Brazilian Tribute to Nasum: Mieszko Lives."

Devastação Sob Terror is a grindcore band from São José dos Campos, São Paulo, Brazil, formed in 2008. The band plays fast, violent grindcore with influences from death metal, crust, and hardcore punk, releasing records including "Campo Minado de Atos Covardes" (2010) and "Legado de Tortura e Escravidão" (2016). They have been active in the São Paulo underground scene and participated in events such as the local Faces of Death festival.

Diagnose is a political grindcore band from Fortaleza, Ceará, in northeastern Brazil, blending elements of crust punk, grindcore, and death metal with socially charged, anti-system lyrical content. The band released the demo "Desordem Capital" in 1998 and has built a discography spanning several decades, including the albums "Neurose XXI" (2005) and "Cidade Objeto" (2021). They are among the more enduring extreme underground acts from the Brazilian northeast.

Discurso de Pobre is a grindcore band from the Paraisópolis periphery of São Paulo, Brazil, combining extreme music with direct social and political commentary. They released the album "Notícia ruim não chega, ela permanece" in May 2018 and followed it with "Tapando o sol com a peneira" in October 2020, both available on Bandcamp. The band operates on a DIY basis within São Paulo's underground grindcore community.

Disespero is an anarcho noisegrind band from Rio de Janeiro, Brazil, formed in June 2018, drawing influence from acts such as Fear of God, AxCx, Cripple Bastards, and Extreme Noise Terror. The band has released several recordings on Bandcamp, including a self-titled album (2019), "Vejo vocês na Disneylândia" (2020), "Uma Odisseia No Descaso" (2021), and "Desabafo" (2024). They operate on a DIY basis and are known for raw, confrontational lyrics rooted in existentialist and anarchic themes.

Disfagia is a one-man death metal and grindcore project from Fortaleza, Ceará, Brazil, created by Victor Viana (also known as Victor Skullcrusher), who handles all instruments. The project began with a crust punk orientation before evolving into a heavier death metal and grindcore sound, with lyrical themes covering war, politics, social issues, and hatred. An early demo, "Puro Desprezo," was recorded in two hours and cites Extreme Noise Terror, Doom, and Disrupt as key influences.

Disfuria is a crust punk and grindcore outfit from Valentín Alsina, Buenos Aires, formed in 2022 and drawing on powerviolence, death metal, and stenchcore. They released their debut full-length "No tengo boca y debo gritar" in December 2022, followed by "Ejercicios de violencia" in October 2023, both available on Bandcamp as independent releases.